Division Director

Craig Criddle is a Professor in the Department of Civil and Environmental Engineering at Stanford University, and a Senior Fellow at the Woods Institute for the Environment. He is the Institutional Co-I for CUBES at Stanford and the lead of the Biofuel and Biomaterials Manufacturing Division of CUBES.

Dr. Criddle is interested in the environmental engineering, science, and science literacy needed for clean water, clean energy, and healthy ecosystems. His research focus is environmental biotechnology. He is best known for large interdisciplinary field projects, studies of microbial
ecology in bioreactors, and work on microbial transformations of persistent contaminants. Some current projects include a field-scale evaluation of uranium remediation; DNA-monitoring of microbial community structure at full-scale biological wastewater treatment plants; development of membrane bioreactors for energy recovery and nutrient removal; and studies to elucidate the mechanisms and kinetics of microbial transformation of halogenated solvents. To promote science literacy, he worked with award-winning San Francisco cartoonist, Larry Gonick to write "The Cartoon Guide to Chemistry." "Cartoons can give us an intuitive feeling for the why, and deeper understanding can grow from that intuition."

Karen A. McDonald headshot
Karen A. McDonald

Karen McDonald is a Professor of Chemical Engineering at the University of California at Davis.  She also serves as the Faculty Director and Co-PI of the UC Davis ADVANCE Institutional Transformation program (, a NSF-funded program to recruit, retain, and advance women STEM faculty.  She is the Institutional Co-I for CUBES at UC Davis and Division Lead for the Food and Pharmaceutical Synthesis Division.

Prior to leading the UC Davis ADVANCE program, she served as Associate Dean for Research and Graduate Studies in the College of Engineering for 13 years. She is a member of the graduate program/groups in Chemical Engineering, Biomedical Engineering, and Plant Biology and is a co-chair of the Designated Emphasis in Biotechnology program.  From 2003-2015 she served as the Co-Director of the NIH Training Grant in Biomolecular Technology at UC Davis, an innovative multidisciplinary research and educational training for doctoral students working at the interface of life sciences and engineering/physical sciences in application areas related to human health. From 2006-2013, she was the PI and Director of the NSF Collaborative Research and Education in Agricultural Technologies and Engineering (CREATE) IGERT, an interdisciplinary graduate training program with Tuskegee University focused on applications of plant biotechnology to biopharmaceuticals, biorefineries and sustainable agriculture.   

Dr. McDonald and her collaborators apply synthetic biology tools in plants for the development of novel expression systems as well as applying bioprocess engineering technologies to produce recombinant proteins (including human therapeutic proteins, enzymes for cellulose degradation, and biopolymers for materials applications) using whole plants, harvested plant tissues, or plant cells grown in vitro in bioreactors. As a biochemical engineer, she is interested in translational research and strives to develop novel biomanufacturing processes that are scalable, cost effective, and meet a variety of design constraints. She has lead large multidisciplinary research teams such as a Defense Threat Reduction Agency-funded project to develop a platform for plant-based production of bioscavengers against biothreat agents.  

Amor Menezes is an Assistant Professor in the Department of Mechanical and Aerospace Engineering at the University of Florida. He is the Science Principal Investigator of the five-year, multi-university, Center for the Utilization of Biological Engineering in Space (CUBES), a NASA Space Technology Research Institute in biomanufacturing for deep space exploration. He also leads the Systems Design and Integration Division of CUBES.

Dr. Menezes' research interests are in dynamical systems theory and control, with applications to the fields of systems biology and synthetic biology. He is an IEEE Senior Member. He was a 2015 Emerging Leader in Biosecurity and a 2015 fellow of the Synthetic Biology Leadership Excellence Accelerator Program.

He was an Associate Project Scientist in the California Institute for Quantitative Biosciences (QB3) at the University of California, Berkeley from 2016 to 2017, and a QB3 Postdoctoral Scholar from 2011 to 2016. He was a Research Fellow between 2010 and 2011 in the Department of Aerospace Engineering at the University of Michigan, where he received a Ph.D. as an NSERC Post-Graduate Scholar and Michigan Teaching Fellow in 2010, and a Master of Science in Engineering as a Milo E. Oliphant Fellow in 2006. He graduated from the University of Waterloo in 2005 with a Bachelor of Applied Science in Mechanical Engineering with Distinction, Dean's Honors (top 10%), and the Sandford Fleming Co-op Medal.

Lance C. Seefeldt is Professor of Chemistry and Biochemistry at Utah State University.  He received his PhD in Biochemistry from the University of California at Riverside and was a Postdoctoral Fellow in the Center for Metalloenzyme Studies at the University of Georgia.  He joined the faculty at Utah State University in 1993.  He is the recipient of the D. Wynne Thorne Research Award and is a Fellow of the American Association for the Advancement of Science.  He is the Utah State University Institutional PI and lead of the Microbial Media and Feedstock Division of CUBES.

Dr. Seefeldt’s research focus is on biological nitrogen fixation.  He has been investigating the mechanism of activation of N2 by the bacterial enzyme nitrogenase.  This work has recently lead to the insight that metal-hydrides are central to the reduction of N2 to NH3.  He is also investigating how to grow nitrogen fixing bacteria with electrodes as a way to accomplish light-driven reduction of N2 and CO2 as a way to capture and make available these resources from the Martian atmosphere.