Robert Waymouth headshot
Robert Waymouth

Robert Waymouth is the Robert Eckles Swain Professor in the Department of  Chemistry at Stanford University. Dr. Waymouth investigates new catalytic strategies to create useful new molecules, including sustainable polymers, synthetic fuels, and bioactive molecules. In one such breakthrough, Professor Waymouth and IBM researcher Jim Hedrick opened a new path for production of environmentally sustainable plastics and improved plastics recycling, earning recognition in the 2012 Presidential Green Chemistry Award.

The Waymouth Group applies mechanistic principles to develop new concepts in catalysis, with particular focus on the development of organometallic and organic catalysts for the synthesis of complex macromolecular architectures. In organometallic catalysis, the group devised a highly selective alcohol oxidation catalyst that selectively oxidizes unprotected polyols and carbohydrates to alpha-hyroxyketones. The Waymouth group pioneered the development of catalysts that can access multiple kinetic states during a polymerization reaction in order to control sequence distribution. They devised a novel strategy for the synthesis of elastomeric polypropylene utilizing a metallocene catalyst whose structure was designed to interconvert between chiral and achiral coordination geometries on the timescale of the synthesis of a single polymer chain.

In collaboration with Jim Hedrick of IBM laboratories, the Waymouth Group has developed an extensive platform of organic catalysts for the controlled ring-opening polymerization of lactones, carbonates and other heterocyclic monomers. Mechanistic studies of nucleophilic N-heterocyclic carbene catalysts revealed an unusual zwitterionic ring-opening polymerization method which enabled the synthesis of high molecular weight cyclic polymers, a novel topology for these biodegradable and biocompatible macromolecules. In collaboration with the Wender group, the Waymouth group has devised selective organocatalytic strategies for the synthesis of functional degradable polymers and oligomers that function as "molecular transporters" to deliver drugs and probes into cells. These efforts combine elements of mechanistic organic and organometallic chemistry, polymer synthesis, and homogeneous catalysis to rationally design new macromolecular structures.

Postdoctoral Scholar

Kristian is an NSERC post-doctoral fellow in Environmental Engineering and Science at Stanford University. His current research focuses on: Hard-wiring bacteria in a microbial battery, salinity gradient energy production from a mixing entropy battery, and PHB bioplastic production from C. Necator. His PhD was in Chemical and Biological Engineering from the University of British Columbia in Vancouver.

Graduate Student

Aaron Berliner is a Bioengineering graduate student in the Arkin Laboratory at UC Berkeley/UCSF. He studied bioengineering, control theory, synthetic and systems biology, and nanotechnology at Boston University. In 2012, he began working as a research associate at the NASA Ames Research Center on projects involving 3D printing, bioelectrochemistry, and astrobiology. In 2013, he started as a research scientist in the Life Sciences group of Autodesk Research in San Francisco. At Autodesk, Aaron’s work ran the gamut from bioprinting, software engineering, synthetic virology, and DNA origami until 2016 when he moved back to space biology. Forming a partnership between UC Berkeley, Autodesk, and NASA Ames, Aaron began construction for Crucible, an open-source reactor for space synthetic biology experiments until 2017 when he started as a graduate student with Adam Arkin. He enjoys playing with his Mars-in-a-jar reactors. Aaron helped author the STRI grant that launched CUBES and is an NSF graduate fellow. His alternative scientific interests are terraforming and radiation biology. Aaron likes whiteboards and dry erase markers and dirty models with clean math.

Matt received his B.S. in Chemical Engineering from the University of Massachusetts, Amherst. He previously worked as a process engineer for Sanofi Genzyme. His current research focuses on developing a novel biologically-derived bioseparations platform for limited resource environments.

Vince is a first-year Ph.D. student in chemistry at Stanford University; he is interested in creating biodegradable organic materials as well as designing materials processing techniques such as additive manufacturing in order to make functional parts from biodegradable materials feasible for replacing petroleum based plastics. His role in CUBES will be to create and optimism polymeric systems based on methanotrophic polyhydroxyalkanoate production for the closed-loop manufacturing of tools. Before starting his graduate work at Stanford, he studied mechanical engineering and chemistry at Colorado School of Mines where he created block copolymer materials for hydrogen fuel cell membranes and computed degradation mechanisms for small molecule bis-azide species. He also worked as a design engineer at RICOH where he designed, 3D printed, and tested small parts for improving large-scale ink-jet printer functions. Vince likes to hike and carve wood in his free time. 

Undergraduate Student

Max Perko is a third year chemistry undergraduate at Stanford, studying biosynthetic polyester vitrimers for additive manufacturing in the Waymouth lab. His research is being performed in conjunction with that of Vince Pane (of the Waymouth lab) and the Criddle lab (Stanford Biology), for the Center for the Utilization of Biological Engineering in Space (CUBES) on their Mars exploration project.

Chris Szikszai
Chris Szikszai
Areas of Interest:

Chris Szikszai worked with the Waymouth group, summer of 2017, testing feasibility of extruding and printing PHBV (poly-3-hydroxybutyrate-co-3-hydroxyvalerate). Aided by Professor Dan Strauss from SJSU and Naomi Clayman, Chris used analytical techniques such as DSC, GPC, and an Instron tensile tester to characterize the biopolymer: before extrusion, prior to printing, and after printing.