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Director

Adam Arkin is the Dean A. Richard Newton Memorial Professor in the Department of Bioengineering at the University of California, Berkeley and Senior Faculty Scientist at the Lawrence Berkeley National Laboratory. He and his laboratory develop experimental and computational technologies for discovery, prediction, control and design of microbial and viral functions and behaviors in environmental contexts.

He is the chief scientist of the Department of Energy Scientific Focus Area, ENIGMA(Ecosystems and Networks Integrated with Genes and Molecular Assemblies, http://enigma.lbl.gov), designed to understand, at a molecular level, the impact of microbial communities on their ecosystems with specific focus on terrestrial communities in contaminated watersheds. He also directs the Department of Energy Systems Biology Knowledgebase (KBase) program: (http://kbase.us) an open platform for comparative functional genomics, systems and synthetic biology for microbes, plants and their communities, and for sharing results and methods with other scientists. He is director of the newly announced Center for Utilization of Biological Engineering in Space which seeks microbial and plant-based biological solutions for in situ resource utilization that reduce the launch mass and improves reliability and quality of food, pharmaceuticals, fuels and materials for astronauts on a mission to Mars. Finally, he is the Co-Director of the Berkeley Synthetic Biology Institute, which brings together U.C. Berkeley and Lawrence Berkeley National Laboratory Scientists with Industry Partners to forward technology and applications for sustainable biomanufacturing.

Faculty

Nils was formerly a member of the academic research staff as part of the Criddle-lab at Stanford University. For CUBES he is developing microbial cell factories that convert C1-carbons into high-performance polymers that can serve as materials for consumables and durable goods. He is also an Analog Astronaut, demonstrating biomanufacturing capabilities in the field (at a Space Exploration Analog and Simulation Habitat), as a proving ground for Mars. Will join University of Florida as assistant professor.

Senior Scientist

Jake hails from the far-away lands of the Midwest. He received his Bachelor's degree in Genetics from the University of Wisconsin-Madison where he was introduced to the world of scientific research through the study of the evolution of gene expression regulation in the yeast Saccharomyces cerevisiae. Upon graduation, Jake began his graduate work in Marine Studies at the University of Delaware where he studied the regulation of energy metabolism in green sulfur bacteria (the Chlorobiaceae). Being a microbiologist that had always admired synthetic biology from a distance, and one that was enamored with space exploration, Jake joined the Arkin Lab at the University of California-Berkeley as a postdoc to pursue applications of microbial engineering to space exploration and colonization. Jake's research interests include environmental microbiology, microbial physiology/systems biology, genetics, synthetic biology, and space bioengineering. 
 

kbsander [AT] berkeley [DOT] edu

Kyle Sander grew up in Portland, Oregon and attended Oregon State University earning a B.S. in Chemical Engineering.  He interned at a Georgia-Pacific Containerboard Mill for a year as an Environmental/Process Engineer, and then went on to earn an M.S. degree in Biological and Ecological Engineering studying life cycle effects of algae production for fuels and co-products. He also investigated rapid sand filtration as an algal dewatering process step and enzymatic degradation of, and simultaneous saccharification and ethanol production from, of algal cell biomass.

Kyle earned his PhD from the University of Tennessee, Knoxville conducting his thesis research within the BioEnergy Science Center at Oak Ridge National Laboratory.  Kyle focused on characterizing and engineering regulatory genes and related cellular redox in two candidate lignocellulolytic, ethanol-producing biocatalysts; Clostridium thermocellum and Caldicellulosiruptor bescii.  Basic redox metabolism was characterized in C. thermocellum, yielding an expanded view of redox metabolism in this organism, as well as a set of promising redox-active metabolic loci which were targeted in subsequent engineering for ethanol yield improvement done by others.  Single-gene deletion mutants of promising regulatory gene targets in C. bescii were generated and screened in bioprocessing-relevant conditions to assess the engineering potential of each gene target.  Deletion of a global redox sensing transcription factor (Rex) enabled C. bescii to synthesize 75% more ethanol and allowed us to comprehensively describe the unique Rex regulon in this organism.  A genotype-phenotype relationship was identified between the FapR local fatty acid biosynthesis repressor and this organism’s tolerance to elevated osmolarity conditions, a highly complex, bioprocess-limiting, and difficult-to-engineer trait.

Outside of the lab, Kyle enjoys running, reading, rock-climbing, spending time with family and friends, and becoming more familiar with his new Berkeley and California surroundings.

Technical Staff

Cassandra is a highly motivated and curious senior undergraduate in the Bioengineering department at UC Berkeley, with a specific focus on cell and tissue engineering. She has previously worked in immunology research, where she formulated antibody-conjugated lipid nanoparticles and assessed their transfection into antigen presenting cells for their possible use as mRNA therapeutic delivery vehicles. She has also worked in polymer research, where she contributed to the standardization of nanoindentation as a modality for retrieval analysis of the polymer component from total knee replacement. Through her coursework and research experiences, she has developed a strong interest in the field of synthetic biology which she hopes to utilize to solve problems caused by the climate crisis, with the increasingly necessary exploration of space being one of these issues. Currently, she is working with Gwyneth Hutchinson and NASA CUBES to engineer Spirulina for pharmaceutical and flavor production with applications for supporting human exploration of space. She hopes that through this work and further research done through a PhD program and beyond, she will be able to assist in finding solutions to climate-related issues. In her free time, you can catch her at the roller rink, or on a hike in the Berkeley hills. She also enjoys crocheting and reading novels.

Postdoctoral Scholar

Dr. Gözde Gülseren is a postdoctoral associate in the Averesch Group at the University of Florida, where she is focused on advancing space-based myco-processing technologies. She earned her B.S. in Food Engineering from Istanbul Technical University (ITU) in Turkiye, and completed her M.S. in Food Engineering and Sustainability through a joint program between ITU, the University of Chemistry and Technology in Prague (Czechia), and Centrale Supélec (France). Dr. Gülseren’s professional experience spans food product development and fermentation, areas in which she has applied her extensive academic training. She received her Ph.D. in Food Science and Human Nutrition from the University of Florida, where her research centered on the functionality of edible mycelia. During her doctoral studies, she was awarded a prestigious INFOGEST Short Term Scientific Mission Grant, enabling her to conduct research at the National Research Institute for Agriculture, Food and Environment (INRAé) in France. Dr. Gülseren's academic and professional achievements have been recognized with numerous honors, including the Silver Celebration Award and a third-place finish in the Student Oral Competition by the Institute of Food Technologists (IFT).
 

Graduate Student

Jackson is primarily interested in the discovery and creation of novel biological systems that can be used in faucets of bioremediation, human health, and space exploration. He has researched bacteriophages in depth, has discovered and annotated novel phages, and has investigated bacteriophage mechanisms of lysis. He has also done bioinformatics work regarding intrinsic disorder in Merkel Cell Polyomavirus and has explored HECTD3's involvement in cancer. He is a proponent of undergraduate research and learning and has developed a program to certify undergraduates in basic lab techniques to better prepare them for academic research. Currently, he is pursuing a PhD at UF and is teaching, taking courses, and working with Dr. Averesch researching bioplastic production.
 

Born and raised in Salt Lake City, Utah. Obtained my bachelor’s in graphic design from the University of Utah where I also commissioned into the US Air Force. Received my master’s in Human Services: Health and Wellness from Liberty University. I am leaving active duty for a couple of years to finish my master’s in microbiology and gain experience in the field.

Katie is a PhD student in the Biomedical Engineering Graduate Group at UC Davis working in the McDonald/Nandi Lab. She received her BS in Biomedical Engineering from the University of Oklahoma, where she worked under the NASA EPSCoR STEM Workforce Development grant to develop targeted nanoparticles for therapeutic delivery. Her current work uses plant viruses to separate antibodies and Fc-fusion proteins from crude feedstocks for the production of biopharmaceuticals in space.

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Gwyneth Hutchinson

Gwyneth graduated from UC Berkeley in 2020 where she did nearly 3 years of research and a fellowship in reproductive neuroendocrinology, chronobiology, and cellular biology. She then transitioned to the UCSF-Gladstone Institute of Neurological Disease where she pursued novel research into the contributions of cellular energy metabolism and bioenergetic failure into neurodegenerative disease pathogenesis. Following this, she worked as a Senior Research Associate at Conception Biosciences where she focused on the development of biotechnologies to turn stem cells into viable eggs for individuals and couples to overcome physiological, age-based, and sexuality-based barriers to reproductive success. With NASA CUBES, Gwyneth is developing innovative approaches to build on the Arkin Lab’s recent successes engineering Spirulina for nutrient, pharmaceutical, and flavor production with applications for supporting human exploration of space. She is devising innovative ways to further improve the efficiency of engineering this previously recalcitrant organism and determining the best routes for metabolic engineering of these critical products. She is also interested in pursuing questions surrounding human physiology and reproduction in space with the goal of improving health outcomes for astronauts and space travelers both during missions and upon return to Earth. When she’s not in the lab, Gwyneth loves to spend time with her puppies—Willow and Pandora—and play guitar. She also fancies herself an amateur shark diver and is on the Board of Directors for a literacy nonprofit.

Lorenzo is a Master's degree student in Agro-food Biotechnology in Verona (IT). He earned his Bachelor's degree in Biotechnology in Pavia (IT) and he works as a research student in Davis. His previous experience mostly concerns plant biotechnology as he worked in molecular biology and protein purification of Zeaxanthin epoxidase.

Vrinda Sharma is a graduate student in the CEE department at Stanford. She is working in the Criddle group on engineering autotrophic microorganisms for P4HB polymer production. She received a B.A. in Biological Sciences from Cornell University in 2022 and worked on impact of biocides like Triclosan on soil microorganisms Stenotrophomonas maltophilia in Hay Lab. Post graduation, she worked as Research Associate I in the Microbial Engineering team in Pivot Bio where she got interested in synthetic biology for environmental applications

Tressa is a PhD candidate in the Biochemistry, Molecular, Cellular and Developmental Biology graduate group at UC Davis. She earned her B.S. in Environmental Systems: Ecology, Evolution and Behavior at UC San Diego. Previously she worked on harnessing microalgae for production of lipids for biofuels, as well as production of recombinant therapeutic proteins. Her current work is focused on producing recombinant therapeutic proteins for use in space by engineering whole plant systems.

Shanice is a PhD student in the Chemical Engineering department at the University of California, Davis, working under Dr. Karen McDonald and Dr. Somen Nandi. She earned her B.S. and M.S. in Chemical Engineering at Northwestern University, and has prior experience with bacterial synthetic biology and metabolic engineering. She worked as a pilot operations engineer at Edwards Lifesciences before returning to school. Her current research involves the purification of pharmaceuticals in transgenic plants within the scope of the NASA CUBES II project.

Outside of research, Shanice enjoys running, hiking, gaming, and arts and crafts.

Undergraduate Student

Milan is an undergraduate student at Rice University studying Electrical and Computer Engineering with a Data Science & Systems specialization. He is interested in utilizing synthetic biology and environmental biotechnology and combining it with artificial intelligence to create sustainable methods of food production, mitigate issues caused by rapid climate change, and assist in deep space exploration.

At CUBES, he is currently working with Dr. Hilzinger to build a cyanobacteria pan genome and utilizing it to understand and analyze the evolution of important phenotypes across different variants (e.g. multicellularity) using machine learning.

Hue is an undergraduate student studying Bioengineering and Electrical Engineering and Computer Science at UC Berkeley. She is interested in exploring the intersection between synthetic and computational biology with hopes of harnessing an application towards enhancing biomedicine and sustainability. She is working with Dr. Hilzinger in the FPSD division of CUBES to help develop innovative approaches toward improving the metabolic engineering of A. platensis for small molecule production. By enhancing the production of pharmaceuticals, nutrients, and flavors in Spirulina, the project aims to support human exploration of space. In her free time, Hue enjoys traveling, watching sunsets at the beach, swimming, and crocheting.

Ishan is a 1st year undergraduate student studying Microbial Biology at UC Berkeley. He is passionate about biopharmaceuticals and its application across diverse fields of study, including in space exploration. Ishan is working under Dr. Hilzinger on the CUBES project to develop genetic tools in A. platensis for improved metabolic engineering. Additionally, he is investigating CRISPR/Cas-9 and its use in developing new plasmids for this bacterium.

Kylie Akiyama is a second-year undergraduate student at UC Berkeley majoring in bioengineering. She is especially interested in the field of synthetic biology and how we can utilize it in the context of space exploration. Kylie is currently within the FPSD division of CUBES, working to improve the group's capacity to metabolically engineer A. platensis for small molecule production.

Snigdha is an undergraduate at UC Berkeley (Class 2025) studying Genetics and Plant Biology. She is working with Dr. Sander on the CUBES project investigating the growth coupling of polyhydroxyalkanoate production in species of Cupriavidus for applications in space exploration. She is interested in studying the genetic engineering of metabolic pathways in bacteria and algae, especially in the broader context of sustainability.

Katie is an undergraduate from New York City studying Bioengineering and Electrical Engineering and Computer Science at UC Berkeley. She is interested in exploring the interdisciplinary connections between computer science and synthetic biology for therapeutic applications. Her past research experience includes altering strain specificity of phage-like molecules and developing small molecule therapeutics for immunosuppression.

Through CUBES, she will be working under the FPSD division towards metabolically engineering A. platensis for small molecule production. Katie hopes to pursue a PhD in Bioengineering after graduation to strength her experimental planning and scientific analysis skills. In her free time, she enjoys trying new foods, traveling, hammocking, crafting, and spending time with friends and family.

Hanen is an undergraduate at UC Berkeley studying Bioengineering. He is interested in utilizing computational and synthetic biology to reduce plastic pollution, develop new drugs and diagnostics, and improve food production and the environment, especially in poorer regions of the world. At CUBE, he is focusing on engineering microbes to produce bioplastics useful for applications in space missions as well as on Earth. 

After undergrad, Hanen plans to pursue a PhD in bioengineering or biotechnology to grow as a scientist. He aims to start a company one day focusing on using bioengineering to address environmental and food insecurity issues around the globe. 

As a San Franciscan native, Hanen enjoys exploring the Bay Area, sports, and reading in his free time. 

 

Justin Wahyudi is an undergraduate student at UC Berkeley studying Bioengineering and Electrical Engineering and Computer Science. Justin is interested in exploring synthetic biology and understanding the various applications that the field offers in healthcare and pharmaceutical settings. He is currently working under Dr. Jacob Hilzinger in the FPSD division of CUBES to help genetically engineer A. platensis for the purpose of pharmaceutical production and supporting advances made in space exploration.

Xina Wang is an undergraduate student at UC Berkeley studying chemical biology and data science. She is interested in the potential of harnessing biosystems found in nature for applications in biomanufacturing and biomedicine through the intersection of synthetic biology and computational tools. Currently, she is engaged in engineering microbes to produce bioplastics for human space exploration as well as for industrial or environmental applications on Earth.

Alumni

Jeremy Adams is a Ph.D. student in Chemical and Biomolecular Engineering at UC Berkeley, currently working in the Clark Lab. He received a BSE in Chemical Engineering from Arizona State University in 2017. Jeremy’s research interests lie in the intersection of synthetic biology and biochemical engineering, particularly towards the development of sustainable biomanufacturing processes. His work in CUBES involves engineering lithoautotrophic microbes to convert Mars-available resources into useful products, as well as engineering export pathways of those products to simplify downstream separation processes. In his free time, Jeremy enjoys traveling and scuba diving.

Sophia is a sophomore at UC Berkeley studying Molecular & Cellular Biology and Economics. She was initially drawn to CUBES because of their work with In-situ Resource Utilization and is interested in studying different forms of life in strenuous environments. In her free time she enjoys surfing, playing soccer and reading novels.

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Brooklyn Brace

Brooklyn Brace is a third year undergraduate student at UC Berkeley studying Molecular and Cell Biology. She has an interest in microbiology and genomics and how they apply to bioengineering. In the Arkin Lab, Brooklyn is currently working in the MMFD division investigating genes important for nitrogen fixation. Previously, Brooklyn worked in a synthetic biology lab at Columbia University working on the development of a multiplexed drug screening platform.

Adam is from Elk Grove, CA, but was born in San Francisco and is well-accustomed to life in the Bay Area. He became interested in engineering when he was very little, building Lego sets and working on home construction projects with his uncle. Not knowing much about bioengineering coming into university, Adam tried learning about different disciplines alongside his initial classes and prioritized gaining skills over hyper-focusing on curriculum, which is where his passion for software engineering developed. His goal is to become a software engineer at a biotech company, so that he can use his programming skills and knowledge of biological systems in tandem to make software and tools that can help the next generation of scientists manipulate and visualize experiments in a more concise and efficient way. Outside of engineering, he loves making art (painting and drawing with any medium he can get his hands on), watching k-dramas and anime, cooking with his friends, and hiking. After graduation, he hopes to travel to places like South Korea and France to learn more about other cuisines and cultures. Adam believes that we all owe it to ourselves to try as many things as possible, so we can find out what we like and don't like to do, and of course where we are exceptional and what needs improvement.

Zain earned a BA in Planetary Science from UC Berkeley. He developed an interest in spaceflight at a young age watching launches at Cape Canaveral. Even as a child he was interested in sustaining human life in space. He hopes to live to see the day when humanity has a permanent Mars colony. On top of his interest in space, Zain has an interest in medicine and hopes to eventually be a physician-scientist. He discovered his interest in medicine after taking biochemistry classes, where he became fascinated by the interconnected chemistry of the human body. In the future, Zain plans to attend medical school and apply in depth knowledge of human biology to space colonization efforts. He joined CUBES just after graduating from UC Berkeley in May 2022. At CUBES, he helps define states for bioastronautics software under Aaron Berliner. In his free time, Zain likes to make music on his guitar and piano, hike, and volunteer with the American Lung Cancer Screening Initiative.

Dr. Coleman-Derr received his graduate education at the University of California at Berkeley in the lab of Dr. Daniel Zilberman in the Plant and Microbial Biology Department, studying mechanisms of epigenetic regulation of transcription in the model plant Arabidopsis. He then completed a post-doctoral research position at the Joint Genome Institute in the group of Dr. Susannah Tringe studying the microbial ecology of the root systems of desert succulents; in this role he also served as bioinformatic support on multiple JGI collaborative metagenomic research efforts involving analysis of 16S rRNA tag data from a variety of environmental and host-associated samples. Dr. Coleman-Derr now leads a research team for the United States Department of Agriculture’s Agricultural Research Service, where he aims to improve our understanding of the effect of abiotic stress on the plant microbiome, and to help identify plant growth promoting microbes capable of alleviating drought stress in their plant hosts. Current research involves several projects related to drought stress response in Sorghum bicolor (sorghum), including investigations into the changes in rhizosphere community composition under drought stress, a genome wide association study to reveal host loci controlled by drought tolerance-inducing root endophytes, and a screen of a collection of cereal endophytes for the ability to confer drought tolerance in sorghum. Dr. Coleman-Derr was awarded the USDA’s Scientist of the Year Award in 2017 for his contributions in this area.
 

Jithran Ekanayake grew up in Sri Lanka and moved to the United States in 2016 to study biology at Carleton College, MN on a Starr Foundation scholarship. He is now a graduate student in the Department of Agricultural and Biological Engineering at the University of Florida, where he works with Dr. Amor Menezes and the Systems Design and Integration Division of CUBES to develop experimentally-validated models of space biomanufacturing processes in low-shear modeled microgravity.

Outside of space synthetic biology, he is interested in pararescue, resilience education, and how space exploration could function as a propellant for the peaceful unification of people and nations across the globe.

Daphne is an undergraduate student at Purdue University studying Engineering Technology Education with minors in Computer Information Technology, Global Studies, Biological Sciences, Biotechnology, and Design & Innovation. She has previously been involved with the HHMI SEA-PHAGES project at Purdue University discovering and characterizing novel bacteriophages. Additionally, she has previously written and edited for a variety of science communication publications.

Within CUBES, she is working with Kyle Sanders on the Numerical Modeling team as a SULI intern, where she is using Julia to analyze relationships within a microbial ecosystem for implantation into the rhizosphere of O. sativa.

Skyler Friedline received his BS in Biochemistry and Molecular Biology from UC Santa Barbara in 2016. He is new to the fields of synthetic biology and microbial engineering but is motivated to learn quickly and make an impact. He began working as a research associate and lab manager in Adam Arkin's UC Berkeley Lab in 2019. He is interested in the development of microbes enabling closed loop living in space and on earth.

Wakuna is a PhD candidate in the environmental engineering program working with Prof. Craig Criddle. Her research focuses on the microbial degradation of methane in mixtures (biogas and natural gas) for the production of biodegradable polymers called polyhydroxyalkanoates (PHAs). Wakuna is interested in understanding the impact these methane mixtures have on microbial communities, the dynamics between the microbial interactions under certain complex conditions, while optimizing the polymer production process and bacterial growth rates. In addition to research, Wakuna is quite passionate about tutoring and mentoring.

Derek F. Harris is a Postdoctoral Fellow in the Seefeldt group at Utah State University. He received a B.S. in biology from Dixie State University and a Ph.D. in biochemistry from Utah State University.

Dr. Harris is interested in the mechanism and evolution of nitrogenase enzymes, as well as applications of nitrogenases unique catalytic properties.

Davian is a second year Berkeley undergrad studying Electrical Engineering and Computer Science. In CUBES, he is working on the interface for space resource modeling software. Davian is also investigating phages in the gut microbiome as part of ENIGMA, and makes vector graphics.

Brendan, originally from Austin, TX, is a second-year chemical engineering major with a concentration in biotechnology. His research interest lies in the intersection of chemical engineering and synthetic biology. As a part of CUBES, Brendan is currently working with postdoctoral scholar Jacob Hilzinger to genetically engineer cyanobacteria to produce useful biomass in both Earth-based and Mars-based economies.

Farrah is a second year undergraduate student studying Bioengineering and Electrical Engineering and Computer Science. In the past, she did computational biology research at UCSD working on genome-scale metabolic modeling. She joined CUBES in late Fall of 2021 working under Aaron Berliner. Currently, Farrah is working with Davian to create a crew-member model that simulates how crew members consume and waste resources during space travel and extravehicular activity.

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Alexander Kamentz

Alexander Kamentz is a 2nd year Ph.D. student in Mechanical Engineering in the SYBORGS Lab under Amor Menezes at the University of Florida. He received his B.S. degree in Mechanical Engineering from the University of Florida in 2019. His research interest is focused around stochastic control theory in the SDID division of CUBES.

Ji Min Kim is a 1st year Ph.D. student in Materials Science and Engineering at the University of California Berkeley in the Yang Group. She received her B.S. degree in Materials Science and Engineering from Hanyang University in 2016 and M.S. degree in Materials Science and Engineering from Seoul National University in 2018. Her research interest is focused on the CO2 fixation via a semiconductor nanowire-bacteria hybrid system in the MMFD division of CUBES. The system utilizing light capturing high surface area nanowire array and acetogenic anaerobes enables the photoelectrochemical acetic acid production with long-term stability.

Anderson Lee is a third-year undergraduate student at UC Berkeley studying Bioengineering with a focus on Synthetic and Computational Biology. He is currently optimizing the production of biopharmaceuticals to be utilized during space travel. In previous companies, he has developed an ELISA procedure to determine the concentration of a tumor-detecting drug in biological samples and enhanced a mobile, quick diagnostic machine that scans for viruses. Previous to the Arkin Lab, he worked in Mohammed Mofrad's Cell and Biomechanics Laboratory at UC Berkeley where he used neural networks with backpropagation to predict a virus' host based on the genome of the virus.

In the future, he sees himself using synthetic biology to conquer problems inherent to the nature of space travel. He believes that technology already present in nature and perfected with evolution can be the key to send humans to other planets.

Jorge is originally from Chicago where he attended Loyola University Chicago and received his B.S. in Environmental Science with a Chemistry Minor. After his undergraduate studies, he attended Stanford where he obtained his M.S. in Environmental Engineering and where he has continued as a PhD student working with Professor Craig Criddle. His research focuses on biotechnology with an emphasis on efficiently utilizing waste streams to produce biological materials (e.g., bioplastics, biofuels). As part of the CUBES effort, Jorge's research involves identifying organisms that can thrive on the limited amount of resources available for long-range space travel.

Kim is a second-year undergraduate student studying Bioengineering. She is interested in the applications of engineering and science in space exploration. In CUBES, she will be working on exploring species of cyanobacteria and developing a pan-genome.

Will is an undergrad at UC Berkeley studying molecular biology and math. He is captivated by the potential of synthetic biology and the application of modern methods of engineering to biology whether in microbes, mammalian cells, or multi-organism communities. In CUBES, Will models and designs microbial communities for agricultural enhancement. Previously, he has worked on metabolic engineering for the production of biofuels and commodity chemicals, directed evolution for the bioremediative degradation of plastic, and microRNA circuits and protein engineering for immunotherapy.

Divya is a third year undergraduate student at UC Berkeley majoring in Bioengineering. She screens Spirulina mutants as they are generated and help in the development of better transformation methods for this organism in FPSD.

Jeffrey Skerker's research focuses on engineering complex traits in microbes using a systems metabolic engineering approach. He has worked on a variety of non-model bacteria and fungi and is particularly interested in developing methods for high-throughput genetics and genome engineering. In the CUBES program, he will help develop Arthrospira platensis (commonly known as Spirulina) as a source of nutrition and medicine. In the initial phase of this project, a basic genetic toolbox will be developed for this organism and then as proof of concept, a two-gene pathway for the production of acetaminophen (i.e. Tylenol) will be integrated into the genome. Although Spirulina is widely grown at the industrial scale as a nutritional supplement, very little strain genetic engineering has been reported in the scientific literature. 

Spencer is originally from Colorado Springs. He received a B.S. in biochemistry from Brigham Young University - Idaho. Currently, he is pursuing a Ph. D in Biochemistry at Utah State University.

Alex Starr is a second year undergraduate at University of California Berkeley with interests in synthetic and molecular biology, applied math, artificial intelligence, and the utilization of biology in space exploration.  As part of CUBES, he is working to develop a system for the detoxification and enrichment of Martian regolith using the perchlorate reducing bacterium Azospira suillum PS.  Prior to joining CUBES, Alex studied expression of genes related to root growth in sunflowers and worked on understanding the genetic basis of drought-tolerant root phenotypes in maize.
 

Kyle Valgardson bachelors of science Biochemistry from Utah Valley University and is currently pursuing a doctorate degree in biochemistry at Utah State University.

Gretchen Vengerova is a third year undergraduate student at UC Berkeley, studying bioengineering. She is interested in applying bioengineering concepts to conservation efforts. Previously she worked at CSU San Marcos, studying the transcriptomics of algae. In CUBES, she is working to study potential loop closure processes in a Martian biomanufactory. In the future, she hopes to use loop closures concepts to decrease terrestrial waste and pollution, but she would also enjoy more opportunities to merge bioengineering with space.

Anya is a graduate student at the University of Florida getting her Ph.D. in Biomedical Engineering with Professor Menezes. Her interests include the application of synthetic biology for medical use in space to better support human space exploration.

Prior to the University of Florida, she received her B.S. in Biomedical Engineering at Columbia University in New York City, where she also competed as the Payload Lead on the university’s rockets team. There, Anya also worked on developing microfluidic devices for cancer diagnostics.

She is originally from Fort Lauderdale, Florida and in her spare time enjoys painting and arts and crafts!

Kelly Wetmore is a graduate student in Adam Arkin’s lab at UC Berkeley with over 15 years of experience in microbial physiology and genetics before and during graduate school. She has been instrumental in developing a number of next-generation tools and protocols for microbial functional genomics. Kelly is supporting the CUBES team in applying these tools to optimize the core biomanufacturing microbes in physiologically more-or-less relevant conditions. She is also part of a large DOE environmental systems biology project in which she is developing a new technology to query high-throughput genetic interactions.

Shunsuke Yamazaki graduated Tokyo University, Japan, where he investigated the mechanism of bacterial lipoprotein transport in the laboratory of Hajime Tokuda. He is then hired Ajinomoto Co., Inc. and joined Research Institute for Bioscience Products and Fine Chemicals, Kawasaki, Japan, where he worked on breeding strains and developing several processes for production of amino-acids and pharmaceuticals. He was currently in charge of investigation of pharmaceutical production using enzymatic conversion process. He became a visiting scholar researcher of Adam Arkin lab at UC Berkeley, CA, USA.

He is currently working as a Researcher with Professor Dr. Lance C. Seefeldt at Utah State University. He received his PhD in Organic Chemistry from Nankai University, Tianjin, China in 2007 and PhD in Biochemistry from Utah State University in 2013. After that, he continuously worked with Dr. Lance Seefeldt as postdoctoral fellow focusing on understanding nitrogenase mechanism with a broad range of interdisciplinary strategies, including biochemical, biophysical, and electrochemical methods. His research interests include metalloenzymes, small molecule activation, and relevant catalyst design and mechanistic studies.

Spencer is a senior at UC Berkeley studying MCB and astrophysics. He joined CUBES in October 2021 and is currently working with Aaron Berliner on an examination of habitability in black hole accretion disks. Outside of astrobiology, Spencer is interested in music and education, and helps direct an organization providing free college admissions prep to communities in the Bay Area. In his spare time, Spencer likes to read, play piano, and game.

Liangzi is a graduate student in Criddle-group at Stanford University. She is working on improving the metabolic function in autotrophic microorganisms to enhance carbon efficiency and produce high-performance bioplastics as part of CUBES.
She is interested in sustainable biomanufacturing, bioremediation, as well as carbon capture and utilization.