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Cubes Resources

Resources

CATEGORIES

In order to better facilitate future developments in the field of space-based biology and in-situ resource utilization, the tools and data developed by CUBES are open to the public to the greatest extent possible. These items are available using the links below.

Journal Articles
Presentations
Software
Data

Journal Articles

Applied Astrobiology: An Integrated Approach to the Future of Life in Space

Robin Wordsworth, Collin Cherubim, Shannon Nangle, Aaron J. Berliner, Esther Dyson, Peter Girguis, David Grinspoon, Rachel Harris, Ken Liu, Adam Marblestone, Chris Mason, Ryan Morhard, Dimitar D. Sasselov, Sara Seager, Robert Wood, and Peter Worden
Astrobiology, 2025
doi: 10.1089/ast.2024.0156
Link | Download

Acetaminophen production in the edible, filamentous cyanobacterium Arthrospira platensis

Jacob M Hilzinger, Skyler Freidline, Divya Sivanandan, Ya-Fang Cheng, Shunsuke Yamazaki, Douglas S Clark, Jeffrey M Skerker, Adam P Arkin
Biotechnology and Bioengineering, 2024
doi: 10.1002/bit.28858
Link | Download

Space Synthetic Biology: A Paradigm for Sustainability on Earth and Beyond

Tiffany J. Vora, Nils J. H. Averesch, Erika A. DeBenedictis, Lynn J. Rothschild
New Space, 2024
doi: 10.1089/space.2024.0002
Link | Download

Nitrogen Accountancy in Space Agriculture

Kevin Yates, Aaron J. Berliner, Georgios Makrygiorgos, Farrah Kaiyom, Matthew J. McNulty, Imran Khan, Paul Kusuma, Claire Kinlaw, Diogo Miron, Charles Legg, James Wilson, Bruce Bugbee, Ali Mesbah, Adam P. Arkin, Somen Nandi, Karen A. McDonald
npj Microgravity, 2024
doi: 10.1038/s41526-024-00428-x
Link | Download

Isolation and Characterization of a Halomonas Species for Non-Axenic Growth-Associated Production of Bio-Polyesters from Sustainable Feedstocks

Sung-Geun Woo, Nils JH Averesch, Aaron J. Berliner, Jörg S. Deutzmann, Vince E. Payne, Sulogna Chatterjee, Craig S. Criddle
Applied Environmental Microbiology , 2024
doi: 10.1128/aem.00603-24
Link | Download

Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight

JangKeun Kim, Braden T. Tierney, Eliah G. Overbey, Ezequiel Dantas, Matias Fuentealba, Jiwoon Park, S. Anand Narayanan, Fei Wu, Deena Najjar, Christopher R. Chin, Cem Meydan, Conor Loy, Begum Mathyk, Remi Klotz, Veronica Ortiz, Khiem Nguyen, Krista A. Ryon, Namita Damle, Nadia Houerbi, Laura I. Patras, Nathan Schanzer, Gwyneth A. Hutchinson, Jonathan Foox, Chandrima Bhattacharya, Matthew Mackay, Evan E. Afshin, Jeremy Wain Hirschberg, Ashley S. Kleinman, Julian C. Schmidt, Caleb M. Schmidt, Michael A. Schmidt, Afshin Beheshti, Irina Matei, David Lyden, Sean Mullane, Amran Asadi, Joan S. Lenz, Omary Mzava, Min Yu, Saravanan Ganesan, Iwijn De Vlaminck, Ari M. Melnick, Darko Barisic, Daniel A. Winer, Sara R. Zwart, Brian E. Crucian, Scott M. Smith, Jaime Mateus, David Furman, Christopher E. Mason
Nature Communications, 2024
doi: 10.1038/s41467-024-49211-2
Link | Download

Advantages of a novel in situ pH measurement for soilless media

Noah James Langenfeld, Hikari Ai Skabelund, Royal Heins, Bruce Bugbee
Frontiers in Plant Science, 2024
doi: 10.3389/fpls.2024.1334328
Link | Download

Space bioprocess engineering as a potential catalyst for sustainability

Gretchen Vengerova, Isaac Lipsky, Gwyneth A. Hutchinson, Nils J. H. Averesch, Aaron J. Berliner
Nature Sustainability, 2024
doi: 10.1038/s41893-024-01305-x
Link | Download

Photons at the ultraviolet-visible interface: Effects on leaf expansion and photoinhibition

Shuyang Zhen, Paul Kusuma, Bruce Bugbee
Scientia Horticulturae , 2024
doi: 10.1016/j.scienta.2023.112785
Link

Improving rice drought tolerance through host-mediated microbiome selection

Alex Styer, Dean Pettinga, Daniel Caddell, Devin Coleman-Derr
Biorxiv (Preprint), 2024
doi: 10.1101/2024.02.03.578672
Link | Download

Domains of life sciences in spacefaring: what, where, and how to get involved

Aaron J. Berliner, Spencer Zezulka, Gwyneth A. Hutchinson, Sophia Bertoldo, Charles S. Cockell, Adam P. Arkin
npj Microgravity, 2024
doi: 10.1038/s41526-024-00354-y
Link | Download

An improved digestion and analysis procedure for silicon in plant tissue

Noah James Langenfeld, Bruce Bugbee
PLOS ONE, 2023
doi: doi.org/10.1371/journal.pone.0289151
Link | Download

Eliminating genes for a two-component system increases PHB productivity in Cupriavidus basilensis 4G11 under PHB suppressing, nonstress conditions

Kyle Sander, Anthony J. Abel, Skyler Friedline, William Sharpless, Jeffrey Skerker, Adam Deutschbauer, Douglas S. Clark, Adam P. Arkin
Biotechnology and Bioengineering, 2023
doi: 10.1002/bit.28532
Link | Download

Approaches to nitrogen fixation and recycling in closed life-support systems

Tyler Wallentine, David Merkley, Noah J. Langenfeld, Bruce Bugbee, Lance C. Seefeldt
Frontiers in Astronomy and Space Sciences, 2023
doi: 10.3389/fspas.2023.1176576
Link | Download

On the contrasting morphological response to far-red at high and low photon fluxes

Paul Kusuma, Bruce Bugbee
Frontiers in Plant Science, 2023
doi: 10.3389/fpls.2023.1185622
Link | Download

Microbial biomanufacturing for space-exploration—what to take and when to make

Nils J.H. Averesch, Aaron J. Berliner, Shannon N. Nangle, Spencer Zezulka , Gretchen L. Vengerova , Davian Ho , Cameran A. Casale , Benjamin A.E. Lehner , Jessica E. Snyder , Kevin B. Clark , Lewis R. Dartnell , Craig S. Criddle , Adam P. Arkin
Nature Communications, 2023
doi: 10.1038/s41467-023-37910-1
Link | Download

Engineering osmolysis susceptibility in Cupriavidus necator and Escherichia coli for recovery of intracellular products

Jeremy David Adams, Kyle B. Sander, Craig S. Criddle, Adam P. Arkin, Douglas S. Clark
Microbial Cell Factories, 2023
doi: 10.1186/s12934-023-02064-8
Link | Download

Toward sustainable space exploration: a roadmap for harnessing the power of microorganisms

Rosa Santomartino, Nils J. H. Averesch, Marufa Bhuiyan, Charles S. Cockell, Jesse Colangelo, Yosephine Gumulya, Benjamin Lehner, Ivanna Lopez-Ayala, Sean McMahon, Anurup Mohanty, Sergio R. Santa Maria, Camilla Urbaniak, Rik Volger, Jiseon Yang, and Luis Zea
Nature Communications, 2023
doi: 10.1038/s41467-023-37070-2
Link | Download

Biological conversion of methane to bioplastics: Kinetics, stoichiometry, and thermodynamic considerations for process optimization

Jorge Luis Meraz, Anthony J. Abel, Douglas S. Clark, Craig S. Criddle
Chemical Engineering Journal, 2023
doi: 10.1016/j.cej.2022.140166
Link | Download

Photosynthesis in rice is increased by CRISPR/Cas9-mediated transformation of two truncated light-harvesting antenna

Daniel Caddell, Noah J. Langenfeld, Madigan JH. Eckels, Shuyang Zhen, Rachel Klaras, Laxmi Mishra, Bruce Bugbee, Devin Coleman-Derr
Frontiers in Plant Science, 2023
doi: 10.3389/fpls.2023.1050483
Link | Download

Photosynthesis in rice is increased by CRISPR/Cas9-mediated transformation of two truncated light-harvesting antenna

Daniel Caddell, Noah J. Langenfeld, Madigan JH. Eckels, Shuyang Zhen, Rachel Klaras, Laxmi Mishra, Bruce Bugbee, Devin Coleman-Derr
Frontiers in Plant Science, 2023
doi: 10.3389/fpls.2023.1050483
Link | Download

Data-Driven Flow-Map Models for Data-Efficient Discovery of Dynamics and Fast Uncertainty Quantification of Biological and Biochemical Systems

Georgios Makrygiorgos, Aaron J. Berliner, Fengzhe Shi, Douglas S. Clark, Adam P. Arkin, Ali Mesbah
Biotechnology and Bioengineering, 2022
doi: 10.1002/bit.28295
Link | Download

Germination and seedling establishment for hydroponics: The benefit of slant boards

Noah James Langenfeld, Bruce Bugbee
PLOS ONE, 2022
doi: 10.1371/journal.pone.0275710
Link | Download

Toward abiotic sugar synthesis from CO2 electrolysis

Stefano Cestellos-Blanco, Sheena Louisia, Michael B.Ross, Yifan Li, Nathan E.Soland, Tyler C. Detomasi, Jessica N. Cestellos Spradlin Daniel K.Nomura, Peidong Yang
Joule, 2022
doi: 10.1016/j.joule.2022.08.007
Link

Principles of Nutrient and Water Management for Indoor Agriculture

Noah James Langenfeld, Daniel Fernandez Pinto, James E. Faust, Royal Heins, Bruce Bugbee
Sustainability, 2022
doi: 10.3390/su141610204
Link | Download

Towards an Extension of Equivalent System Mass for Human Exploration Missions on Mars

Davian Ho, George Makrygiorgos, Avery Hill, Aaron J. Berliner
npj Microgravity, 2022
doi: 10.1038/s41526-022-00214-7
Link | Download

Photosynthesis in sun and shade: the surprising importance of far-red photons

Shuyang Zhen, Marc W. van Iersel, Bruce Bugbee
New Phytologist, 2022
doi: 10.1111/nph.18375
Link

Cultivation of the Dematiaceous Fungus Cladosporium sphaerospermum Aboard the International Space Station and Effects of Ionizing Radiation

Nils J. H. Averesch, Graham K. Shunk, Christoph Kern
Frontiers in Microbiology, 2022
doi: 10.3389/fmicb.2022.877625
Link | Download

Space Bioprocess Engineering on the Horizon

Aaron J. Berliner, Isaac Lipsky, Davian Ho, Jacob M. Hilzinger, Gretchen Vengerova, George Makrygiorgos, Matthew J. McNulty, Kevin Yates, Nils J.H. Averesch, Charles S. Cockell, Tyler Wallentine, Lance C. Seefeldt, Craig S. Criddle, Somen Nandi, Karen A. McDonald, Amor A. Menezes, Ali Mesbah, Adam P. Arkin
Communications Engineering, 2022
doi: 10.1038/s44172-022-00012-9
Link | Download

Enhancing Biohybrid CO2 to Multicarbon Reduction via Adapted Whole-Cell Catalysts

Jimin Kim, Stefano Cestellos-Blanco, Yue-xiao Shen, Rong Cai, Peidong Yang
Nano Letters, 2022
doi: 10.1021/acs.nanolett.2c01576
Link | Download

Plant-based Production and Characterization of a Promising Fc-fusion Protein against Bone Mass Density Loss

Yongao Xiong, Hiroto Hirano, Nancy E. Lane, Somen Nandi, Karen A. McDonald
Frontiers in Bioengineering and Biotechnology, 2022
doi: 10.3389/fbioe.2022.962292
Link | Download

A comparative life cycle analysis of electromicrobial production systems

Anthony J. Abel, Jeremy David Adams, Douglas S. Clark
Energy & Environmental Science, 2022
doi: 10.1039/D2EE00569G
Link | Download

Charting a narrow course for direct electron uptake-facilitated electromicrobial production

Anthony J. Abel, Jeremy D. Adams, Jacob M. Hilzinger, Adam P. Arkin
bioRxiv, 2022
doi: 10.1101/2022.05.28.493842
Link | Download

Affinity sedimentation and magnetic separation with plant-made immunosorbent nanoparticles for therapeutic protein purification

Matthew J. McNulty, Anton Schwartz, Jesse Delzio, Kalimuthu Karuppanan, Aaron Jacobson, Olivia Hart, Abhaya Dandekar, Anatoli Giritch, Somen Nandi, Yuri Gleba, Karen A. McDonald
Frontiers in Bioengineering and Biotechnology , 2022
doi: 10.3389/fbioe.2022.865481
Link | Download

Photovoltaics-Driven Power Production Can Support Human Exploration on Mars

Anthony J. Abel, Aaron J. Berliner, Mia Mirkovic, William D. Collins, Adam P. Arkin, Douglas S. Clark
Frontiers in Astronomy and Space Sciences, 2022
doi: 10.3389/fspas.2022.868519
Link | Download

Photosynthetic biohybrid coculture for tandem and tunable CO2 and N2 fixation

Stefano Cestellos-Blanco, Rachel R. Chan, Yue-xiao Shen, Ji Min Kim, Tom A. Tacken, Rhesa Ledbetter, Sunmoon Yu, Lance C. Seefeldt, Peidong Yang
PNAS, 2022
doi: 10.1073/pnas.2122364119
Link | Download

Introducing Uncertainty Quantification to Techno-economic Models of Manufacturing Field-Grown Plant-Made Products

Matthew J. McNulty, Kirolos Kelada, Debashis Paul, Somen Nandi, Karen A. McDonald
Food and Bioproducts Processing, 2022
doi: 10.1016/j.fbp.2021.04.013
Link | Download

Phylogenetic diversity of NO reductases, new tools for NOR monitoring, and insights into N2O production in natural and engineered environments

Sung-Geun Woo, Holly L. Sewell, Craig S. Criddle
Frontiers of Environmental Science & Engineering, 2022
doi: 10.1007/s11783-022-1562-3
Link | Download

Performance-Oriented Model Learning for Control via Multi-Objective Bayesian Optimization

Georgios Makrygiorgos, Angelo D. Bonzanini, Victor Miller, Ali Mesbah
Computers & Chemical Engineering, 2022
doi: 10.1016/j.compchemeng.2022.107770
Link

Functionalizing silica sol-gel with entrapped plant virus-based immunosorbent nanoparticles

Matthew J. McNulty, Naomi Hamada, Jesse Delzio, Liber McKee, Somen Nandi, Marjorie L. Longo, Karen A. McDonald
Journal of Nanobiotechnology, 2021
doi: 10.1186/s12951-022-01303-1
Link | Download

Systems-informed genome mining for electroautotrophic microbial production

Anthony J. Abel, Jacob M. Hilzinger, Adam P. Arkin, Douglas S. Clark
Bioelectrochemistry, 2022
doi: 10.1016/j.bioelechem.2022.108054
Link | Download

Adversarially robust Bayesian optimization for efficientauto-tuning of generic control structures under uncertainty

Joel A. Paulson, Georgios Makrygiorgos, Ali Mesbah
AIChe Journal, 2022
doi: 10.1002/aic.17591
Link | Download

Biocatalytic Formation of Novel Polyesters with para-Hydroxyphenyl groups in the Backbone – Engineering Cupriavidus necator for production of high-performance materials from CO2 and electricity

Nils J.H. Averesch, Vince E. Pane, Frauke Kracke, Marika Ziesack, Shannon N. Nangle, Pamela A. Silver, Robert W. Waymouth, Craig S. Criddle
bioRxiv, 2021
doi: 10.1101/2021.12.12.472320
Link | Download

Colorimetric determination of urea using diacetyl monoxime with strong acids

Noah James Langenfeld, Lauren Elizabeth Payne, Bruce Bugbee
PLOS ONE, 2021
doi: 10.1371/journal.pone.0259760
Link

Toward an optimal spectrum for photosynthesis and plant morphology in LED-based crop cultivation

Shuyang Zhen, Paul Kusuma, Bruce Bugbee
Plant Factory Basics, Applications and Advances, 2021
doi: 10.1016/B978-0-323-85152-7.00018-5
Link | Download

Techno-economic process modelling and Monte Carlo simulation data of uncertainty quantification in field-grown plant-based manufacturing

Matthew J McNulty, Kirolos Kelada, Debashis Paul, Somen Nandi, Karen A McDonald
Data in Brief, 2021
doi: 10.1016/j.dib.2021.107317
Link | Download

Evaluating the cost of pharmaceutical purification for a long-duration space exploration medical foundry

Matthew J. McNulty, Aaron J. Berliner, Patrick G. Negulescu, Liber McKee, Olivia Hart, Kevin Yates, Adam P. Arkin, Somen Nandi, Karen A. McDonald
Frontiers in Microbiology, 2021
doi: 10.3389/fmicb.2021.700863
Link | Download

Contributions of the international plant science community to the fight against infectious diseases in humans—part 2: Affordable drugs in edible plants for endemic and re-emerging diseases

Wenshu He, Can Baysal, Maria Lobato Gómez, Xin Huang, Derry Alvarez, Changfu Zhu, Victoria Armario-Najera, Aamaya Blanco Perera, Pedro Cerda Bennaser, Andrea Saba-Mayoral, Guillermo Sobrino-Mengual, Ashwin Vargheese, Rita Abranches, Isabel Alexandra Abreu, Shanmugaraj Balamurugan, Ralph Bock, Johannes F. Buyel, Nicolau B. da Cunha, Henry Daniell, Roland Faller, André Folgado, Iyappan Gowtham, Suvi T. Häkkinen, Shashi Kumar, Ramalingam Sathish Kumar, Cristiano Lacorte, George P. Lomonossoff, Ines M. Luís, Julian K.-C. Ma, Karen A. McDonald, Andre Murad, Somen Nandi, Barry O’Keef, Subramanian Parthiban, Mathew J. Paul, Daniel Ponndorf, Elibio Rech, Julio C.M. Rodrigues, Stephanie Ruf, Stefan Schillberg, Jennifer Schwestka, Priya S. Shah, Rahul Singh, Eva Stoger, Richard M. Twyman, Inchakalody P. Varghese, Giovanni R. Vianna, Gina Webster, Ruud H. P. Wilbers, Paul Christou, Kirsi-Marja Oksman-Caldentey, Teresa Capell
Plant Biotechnology Journal, 2021
doi: 10.1111/pbi.13658
Link | Download

Molecular insights and future frontiers in cell photosensitization for solar-driven CO2 conversion

Stefano Cestellos-Blanco, Ji Min Kim, Nicholas George Watanabe, Rachel Rebecca Chan, Peidong Yang
iScience, 2021
doi: 10.1016/j.isci.2021.102952
Link | Download

A Data-Driven Automatic Tuning Method for MPC under Uncertainty using Constrained Bayesian Optimization

Farshud Sorourifar, Georgios Makrygiorgos, Ali Mesbah, Joel A.Paulson
16th IFAC Symposium on Advanced Control of Chemical Processes, 2021
doi: 10.1016/j.ifacol.2021.08.249
Link | Download

Envisioning the “Air Economy” — Powered by Reticular Chemistry and Sunlight for Clean Air, Clean Energy, and Clean Water

Peidong Yang, Douglas S. Clark, Omar M. Yaghi
Molecular Frontiers Journal, 2021
doi: 10.1142/S2529732521400046
Link | Download

Photons from NIR LEDs can delay flowering in short-day soybean and Cannabis: Implications for phytochrome activity

Paul Kusuma , F. Mitchell Westmoreland, Shuyang Zhen, Bruce Bugbee
PLOS ONE, 2021
doi: 10.1371/journal.pone.0255232
Link | Download

Production of PHB from CO2-derived acetate with minimal processing assessed for space biomanufacturing

Stefano Cestellos-Blanco, Skyler Friedline, Kyle B. Sander, Anthony J. Abel, Ji Min Kim, Douglas S. Clark, Adam P. Arkin, Peidong Yang
Frontiers in Microbiology, 2021
doi: doi: 10.3389/fmicb.2021.700010
Link | Download

Liquid Sunlight: The Evolution of Photosynthetic Biohybrids

Peidong Yang
Nano Letters, 2021
doi: 10.1021/acs.nanolett.1c02172
Link | Download

Towards a Biomanufactory on Mars

Aaron J. Berliner, Jacob M. Hilzinger , Anthony J. Abel , Matthew McNulty , George Makrygiorgos , Nils J.H. Averesch , Soumyajit Sen Gupta , Alexander Benvenuti , Daniel Caddell , Stefano Cestellos-Blanco , Anna Doloman , Skyler Friedline , Davian Ho , Wenyu Gu , Avery Hill , Paul Kusuma , Isaac Lipsky , Mia Mirkovic , Jorge Meraz , Vince Pane , Kyle B. Sander , Fengzhe Shi , Jeffrey M. Skerker , Alexander Styer , Kyle Valgardson , Kelly Wetmore , Sung-Geun Woo , Yongao Xiong , Kevin Yates , Cindy Zhang , Shuyang Zhen , Bruce Bugbee , Devin Coleman-Derr , Ali Mesbah , Somen Nandi , Robert W. Waymouth , Peidong Yang , Craig S. Criddle , Karen A. McDonald , Amor A. Menezes , Lance C. Seefeldt , Douglas S. Clark , Adam P. Arkin
Frontiers in Astronomy and Space Sciences, 2021
doi: doi: 10.3389/fspas.2021.711550
Link | Download

Contributions of the international plant science community to the fight against human infectious diseases – part 1: epidemic and pandemic diseases

Maria Lobato Gómez, Xin Huang, Derry Alvarez, Wenshu He, Can Baysal, Changfu Zhu, Victoria Armario-Najera, Amaya Blanco Perera, Pedro Cerda Bennasser, Andera Saba-Mayoral, Guillermo Sobrino-Mengual, Ashwin Vargheese, Rita Abranches, Isabel Alexandra Abreu, Shanmugaraj Balamurugan, Ralph Bock, Johannes.F. Buyel, Nicolau B. da Cunha, Henry Daniell, Roland Faller, André Folgado, Iyappan Gowtham, Suvi T. Häkkinen, Shashi Kumar, Sathish Kumar Ramalingam, Cristiano Lacorte, George P. Lomonossoff, Ines M. Luís, Julian K.-C. Ma, Karen. A. McDonald, Andre Murad, Somen Nandi, Barry O’Keefe, Kirsi-Marja Oksman-Caldentey, Subramanian Parthiban, Mathew J. Paul, Daniel Ponndorf, Elibio Rech, Julio C. M. Rodrigues, Stephanie Ruf, Stefan Schillberg, Jennifer Schwestka, Priya S. Shah, Rahul Singh, Eva Stoger, Richard M. Twyman, Inchakalody P. Varghese, Giovanni R. Vianna, Gina Webster, Ruud H. P. Wilbers, Teresa Capell, Paul Christou
Plant Biotechnology Journal, 2021
doi: 10.1111/pbi.13657
Link | Download

Why Far-Red Photons Should Be Included in the Definition of Photosynthetic Photons and the Measurement of Horticultural Fixture Efficacy

Shuyang Zhen, Marc van Iersel, Bruce Bugbee
Frontiers in Plant Science, 2021
doi: 10.3389/fpls.2021.693445
Link | Download

Choice of microbial system for in-situ resource utilisation on Mars

Nils J.H. Averesch
Frontiers in Astronomy and Space Sciences, 2021
doi: doi: 10.3389/fspas.2021.700370
Link | Download

Optimizing nitrogen fixation and recycling for food production in regenerative life support systems

Noah Langenfeld, Paul Kusuma, Tyler Wallentine, Craig Criddle, Lance C. Seefeldt, Bruce Bugbee
Frontiers in Astronomy and Space Sciences, 2021
doi: doi: 10.3389/fspas.2021.699688
Link | Download

Evaluation of Three Electrochemical Dissolved Oxygen Meters

Noah J. Langenfeld, Bruce Bugbee
HortTechnology, 2021
doi: 10.21273/HORTTECH04819-21
Link | Download

Improving the Predictive Value of Phytochrome Photoequilibrium: Consideration of Spectral Distortion Within a Leaf

Paul Kusuma, Bruce Bugbee
Frontiers in Plant Science, 2021
doi: doi.org/10.3389/fpls.2021.596943
Link | Download

Does Green Really Mean Go? Increasing the Fraction of Green Photons Promotes Growth of Tomato but Not Lettuce or Cucumber

Paul Kusuma, Boston Swan, Bruce Bugbee
Plants, 2021
doi: doi.org/10.3390/plants10040637
Link | Download

Molecular pharming to support human life on the moon, mars, and beyond

Matthew J. McNulty, Yongao (Mary) Xiong, Kevin Yates, Kalimuthu Karuppanan, Jacob M. Hilzinger, Aaron J. Berliner, Jesse Delzio, Adam P. Arkin, Nancy E. Lane, Somen Nandi, Karen A. McDonald
Critical Reviews in Biotechnology, 2021
doi: doi.org/10.1080/07388551.2021.1888070
Link | Download

Alpha-1 antitrypsin deficiency and recombinant protein sources with focus on plant sources: Updates, challenges and perspectives

Matthew J.McNulty, David Z.Silberstein, Brooks T.Kuhn, Hal S.Padgett, SomenNandi, Karen A.McDonald, Carroll E.Cross
Free Radical Biology and Medicine Volume, 2021
doi: doi.org/10.1016/j.freeradbiomed.2020.11.030
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Fast approximate learning-based multistage nonlinear model predictive control using Gaussian processes and deep neural networks

Angelo D.Bonzanini, Joel A.Paulson, GeorgiosMakrygiorgos, AliMesbah
Computers & Chemical Engineering, 2021
doi: doi.org/10.1016/j.compchemeng.2020.107174
Link | Download

Tractable Global Solutions to Bayesian Optimal Experiment Design

Diogo Rodrigues, Georgios Makrygiorgos, Ali Mesbah
59th IEEE Conference on Decision and Control, 2020
doi: DOI: 10.1109/CDC42340.2020.9304226
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Far-red Fraction: An Improved Metric for Characterizing Phytochrome Effects on Morphology

Paul Kusuma, Bruce Bugbee
Journal of the American Society for Horticultural Science, 2020
doi: doi.org/10.21273/JASHS05002-20
Link | Download

The Emergency Response Capacity of Plant-Based Biopharmaceutical Manufacturing-What It Is and What It Could Be

Daniel Tuse, Somen Nandi, Karen A. McDonald, Johannes Felix Buyel
Frontiers in Plant Science, 2020
doi: doi.org/10.3389/fpls.2020.594019
Link | Download

A Comprehensive Modeling Analysis of Formate-Mediated Microbial Electrosynthesis

Anthony J. Abel, Douglas S. Clark
ChemSusChem, 2020
doi: doi.org/10.1002/cssc.202002079
Link | Download

Steady-state stomatal responses of C3 and C4 species to blue light fraction: Interactions with CO2 concentration

Shuyang Zhen, Bruce Bugbee
Plant, Cell & Environment, 2020
doi: doi.org/10.1111/pce.13888
Link | Download

Substituting Far-Red for Traditionally Defined Photosynthetic Photons Results in Equal Canopy Quantum Yield for CO2 Fixation and Increased Photon Capture During Long-Term Studies: Implications for Re-Defining PAR

Shuyang Zhen, Bruce Bugbee
Frontiers in Plant Science, 2020
doi: doi.org/10.3389/fpls.2020.581156
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An Experimentally Evaluated Thermodynamic Approach to Estimate Growth of Photoheterotrophic Purple Non-sulfur Bacteria

Anna Doloman, Lance C. Seefeldt
Frontiers in Microbiology, 2020
doi: doi.org/10.3389/fmicb.2020.540378
Link | Download

Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion proteins and their interaction with the SARS-CoV-2 spike protein binding domain

Austen Bernardi, Yihan Huang, Bradley Harris, Yongao Xiong, Somen Nandi, Karen A. McDonald, Roland Faller
PLOS ONE, 2020
doi: doi.org/10.1371/journal.pone.0237295
Link | Download

Design of Anaerobic Digestion Systems for Closed Loop Space Biomanufacturing

Alexander Benvenuti, Saige Drecksler, Soumyajit Sen Gupta, Amor A. Menezes
International Conference on Environmental Systems, 2020
doi: hdl.handle.net/2346/86374
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Effects of Space Biomanufacturing on Fuel Production Alternatives for Mars Exploration

Saige Drecksler, Soumyajit Sen Gupta, Alexander Benvenuti, Amor A. Menezes
International Conference on Environmental Systems , 2020, 2020
doi: hdl.handle.net/2346/86375
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Providing photons for food in regenerative life support: A comparative analysis of solar fiber optic and electric light systems

J. Matthew Hardy, Paul Kusuma, Bruce Bugbee, Ray Wheeler, Michael Ewert
International Conference on Environmental Systems , 2020
Link | Download

From Farm to Finger Prick—A Perspective on How Plants Can Help in the Fight Against COVID-19

Karen A. McDonald, R. Barry Holtz
Frontiers in Bioengineering and Biotechnology, 2020
doi: doi.org/10.3389/fbioe.2020.00782
Link | Download

Fast Probabilistic Uncertainty Quantification and Sensitivity Analysis of a Mars Life Support System Model

GeorgiosMakrygiorgos, Soumyajit SenGupta, Amor A.Menezes, Ali Mesbah
21st IFAC World Congress, 2020
doi: doi.org/10.1016/j.ifacol.2020.12.563
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Surrogate modeling for fast uncertainty quantification: Application to 2D population balance models

Georgios Makrygiorgos, Giovanni Maria Maggionib, Ali Mesbah
Computers & Chemical Engineering, 2020
doi: doi.org/10.1016/j.compchemeng.2020.106814
Link | Download

Technoeconomic analysis of semicontinuous bioreactor production of biopharmaceuticals in transgenic rice cell suspension cultures

Jasmine M. Corbin, Matthew J. McNulty, Kantharakorn Macharoen, Karen A. McDonald, Somen Nandi
Biotechnology and Bioengineering, 2020
doi: doi.org/10.1002/bit.27475
Link | Download

Membrane and Fluid Contactors for Safe and Efficient Methane Delivery in Methanotrophic Bioreactors

Jorge Luis Meraz, Kristian L. Dubrawski, Sahar H. El Abbadi, Kwang-Ho Choo, Craig S. Criddle
Journal of Environmental Engineering, 2020
doi: DOI: 10.1061/(ASCE) EE.1943-7870.0001703
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Photosynthetic semiconductor biohybrids for solar-driven biocatalysis

Stefano Cestellos-Blanco, Hao Zhang, Ji Min Kim, Yue-xiao Shen, Peidong Yang
Nature Catalysis, 2020
doi: doi.org/10.1038/s41929-020-0428-y
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Close-Packed Nanowire-Bacteria Hybrids for Efficient Solar-Driven CO2 Fixation

Yude Su, Stefano Cestellos-Blanco, Ji Min Kim, Yue-xiao Shen, Qiao Kong, Dylan Lu, Chong Liu, Hao Zhang, Yuhong Cao, Peidong Yang
Joule, 2020
doi: doi.org/10.1016/j.joule.2020.03.001Get
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From physics to fixtures to food: current and potential LED efficacy

Paul Kusuma, P. Morgan Pattison, Bruce Bugbee
Horticulture Research, 2020
doi: doi.org/10.1038/s41438-020-0283-7
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Far-red photons have equivalent efficiency to traditional photosynthetic photons: Implications for redefining photosynthetically active radiation

Shuyang Zhen, Bruce Bugbee
Plant, Cell & Environment, 2020
doi: doi.org/10.1111/pce.13730
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Phototrophic N2 and CO2 Fixation Using a Rhodopseudomonas palustris-H2 Mediated Electrochemical System With Infrared Photons

Mathangi Soundararajan,Rhesa Ledbetter, Paul Kusuma, Shuyang Zhen, Paul Ludden, Bruce Bugbee, Scott A. Ensign, Lance C. Seefeldt
Frontiers in Microbiology, 2019
doi: doi.org/10.3389/fmicb.2019.01817
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Can biotechnology turn the tide on plastics?

Anja Malawi Brandon, Craig S Criddle
Current Opinion in Biotechnology, 2019
doi: doi.org/10.1016/j.copbio.2019.03.020
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Solar-driven carbon dioxide fixation using photosynthetic semiconductor bio-hybrids

Stefano Cestellos-Blanco, Hao Zhang, Peidong Yang
Faraday Discussions, 2019
doi: DOI: 10.1039/c8fd00187a
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Cytoprotective metal-organic frameworks for anaerobic bacteria

Zhe Ji, Hao Zhang, Hao Liu, Omar M. Yaghi, Peidong Yang
Proceedings Of The National Academy Of Sciences, 2018
doi: doi.org/10.1073/pnas.1808829115
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Glycoform Modification of Secreted Recombinant Glycoproteins through Kifunensine Addition during Transient Vacuum Agroinfiltration

Yongao Xiong, Qiongyu Li, Muchena J. Kailemia, Carlito B. Lebrilla, Somen Nandi, Karen A. McDonald
International Journal of Molecular Sciences, 2018
doi: doi: 10.3390/ijms19030890
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LEDs for photons, physiology and food

P. M. Pattison, J. Y. Tsao, G. C. Brainard, Bruce Bugbee
Nature, 2018
doi: https://doi.org/10.1038/s41586-018-0706-x
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Economics of LED Lighting

Bruce Bugbee
Light Emitting Diodes for Agriculture, 2017
doi: 10.1007/978-981-10-5807-3_5
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Presentations

Software

CUBES GitHub

Aaron J. Berliner, Davian Ho, Avery Hill, Mia Mirkovic, Isaac Lipsky, George Makrygiorgos, Fengzhe Shi, Soumyajit Sen Gupta, Adam Arkin
Link

Data

LEDs for Extraterrestrial Agriculture: Tradeoffs between Color Perception and Photon Efficacy

Paul Kusuma, Brendan Fatzinger, Bruce Bugbee, Wouter Soer, Raymond Wheeler
NASA STI Program Report Series, 2021
doi: NASA/TM-20210016720
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Industry News

USU Scientists Among Multi-Institution Team Receiving NASA Achievement Award

News

https://www.usu.edu/today/story/usu-scientists-among-multi-institution-team-receiving-nasa-achievement-award

Food on Mars, food on Earth: NASA taps USU scientists for space quest

News

Can earthlings live on Mars? They can if they develop self-sufficiency. NASA is betting on a multi-institution team of the best and brightest, including Utah State University scientists, to create the necessary technology and put it in the hands of future Mars pioneers.

Mars Pioneers

NASA Funds 2 New Research Institutes to Help Humanity Explore Deep Space

News

NASA will spend up to $30 million over the next five years to set up and support two new institutes dedicated to helping humanity extend its footprint out into the solar system.

Expanding talent base through space

A Synthetic Biology Architecture to Detoxify and Enrich Mars Soil for Agriculture

News

NASA's initial press release for CUBES-related innovative advanced concept grant!

Promise for the future

NASA Selects Proposals for First-Ever Space Technology Research Institutes

News

NASA has selected proposals for the creation of two multi-disciplinary, university-led research institutes that will focus on the development of technologies critical to extending human presence deeper into our solar system.

Extending into space

The Center for the Utilization of Biological Engineering in Space (CUBES)

News

NASA's initial description of the Center for the Utilization of Biological Engineering in Space!

Biomanufacturing in space

CUBES' Devin Colemann Derr Named USDA ARS Western Regional Scientist of the Year 2017

News
FPSD
NASA STRI
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